Jobs for Humanity is partnering with Guidehouse to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located.

Company Name: Guidehouse

Job Family:

Scientist (Digital)

Travel Required:

None

Clearance Required:

Ability to Obtain Public Trust

What You Will Do:
We are currently searching for a Scientist (Chemist) to independently provide support services to satisfy the overall operational objectives of the National Center for Advancing Translational Sciences (NCATS), Therapeutics Development Branch (TDB). This is a full-time, on-site opportunity in Rockville, MD.  

• Perform synthetic route scouting.
• Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
• Maintain up-to-date electronic laboratory notebook detailing all experiments.
• Gather, analyze and interpret data; prepare summaries and reports.
• Search chemical databases for journal articles, patents and related technologies.
• Perform chemical and biochemical reactions and appropriate analytical analyses.
• Perform analytical validation and testing of compositions.
• Perform general maintenance and upkeep of equipment and instrumentation.
• Troubleshoot and provide routine maintenance of the instruments and equipment.
• Monitor, troubleshoot and initiate or take corrective action to maintain instrument function and quality.
• Identify the cause of common problems and mistakes and make necessary repairs.
• Write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals.
• Collect and review data; analyze and interpret data and results.
• Produce research reports and communicate results.
• Formulate chemistry plans for the development of soluble, potent, selective small molecule probes of biological function.
• Analyze samples using validated analytical methods for ongoing studies.
• Perform the total syntheses of target compounds.
• Manage bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
• Perform chemical synthesis and optimization of small molecule probes for use in biological research.
• Perform organic synthesis of key materials (e.g., reference compounds and precursors for labeling).
• Perform organic synthesis in support of the medicinal chemistry program.
• Perform solid state analysis of target compounds.
• Purify compounds by preparative chromatography from chemists.
• Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
• Perform analytical validation and testing of compositions.
• Prepare reagents and maintain an active inventory of all chemicals kept in the laboratory.
• Keep an active inventory of all chemicals kept in the laboratory.
• Perform analytical validation and testing of compositions and report results.
• Maintain computer database for various records.
• Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
• Develop new analytical and separation techniques for the solution of scientific questions.
• Perform analytical validation and testing of compositions.
• Develop and document new procedures.
• Develop novel chemistry methodologies and technologies that advance the field and make recommendations.
• Collaborate with staff to evaluate and/or develop new techniques.
• Develop and present plans for novel syntheses and approaches to new compounds.
• Develop experimental procedures and research protocols.
• Develop and present plans for novel syntheses and approaches to new compounds.
• Carry out scale-up of the chemical probes of interest for additional studies.
• Maintain and perform training on scientific instrumentation and equipment.
• Work with staff on all mandatory training and competency assessments.
• Coordinate safety training (e.g., CPR and fire extinguisher use).
• Work with facilities manager on evacuation procedures and drills.

What You Will Need:

• Master’s degree
• At least 1 year of experience

What Would Be Nice To Have:

• Good Manufacturing Practice (GMP)
• Microscopy: Confocal, Electron, Multi-Photon, Fluorescence, Super Resolution Nuclear Magnetic Resonance
• Thin-layer chromatography
• X-Ray crystallography
• Manuscript writing
• Mass Spectrometry
• Spectrophotometry
• Thermal analytical technologies
• Chromatography technologies (HPLC, UPLC, GC, IC)
• Kilo Lab or pilot plant experience
• MS Office including Outlook, PowerPoint, Project, Outlook, Excel, Word

#SOAR#LI-FG1

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical, Rx, Dental & Vision Insurance

• Personal and Family Sick Time & Company Paid Holidays

• Parental Leave

• 401(k) Retirement Plan

• Group Term Life and Travel Assistance

• Voluntary Life and AD&D Insurance

• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

• Transit and Parking Commuter Benefits

• Short-Term & Long-Term Disability

• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

• Employee Referral Program

• Corporate Sponsored Events & Community Outreach

• Care.com annual membership

• Employee Assistance Program

• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse
Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [email protected]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.