Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Job Description

We are seeking a highly accomplished Staff Software Engineer to lead the design and delivery of scalable, cloud-native platforms across enterprise and integration ecosystems. This role requires deep expertise in AWS cloud architecture, Java/Python development, and enterprise integration patterns, along with a focus on AI/ML-driven solutions.

Key Responsibilities

• Design and develop scalable systems using Java and/or Python
• Architect cloud-native solutions on AWS
• Build enterprise integration frameworks using APIs and event-driven patterns
• Develop microservices and distributed systems
• Integrate enterprise platforms like Salesforce and third-party systems
• Develop AI-powered solutions for automation and insights
• Ensure system scalability, security, and performance
• Drive CI/CD and engineering best practices
• Mentor engineers and provide leadership

Duties and Responsibilities:

Must Have

• Design and execute test strategies for data pipelines and analytics systems
• Perform end-to-end data validation including source-to-target reconciliation
• Write complex SQL queries (CTEs, joins, aggregations, window functions) for validating
transformations
• Validate business logic and ensure data accuracy across layers
• Validate Tableau dashboards including KPIs, filters, calculated fields, and data consistency
• Collaborate with data engineers, product managers, and stakeholders
• Build automation scripts using Python for data validation and regression
• Collaborate with data engineering teams to validate data platform functionality
• Experience working with CI/CD pipelines (e.g., Jenkins, GitHub Actions) and automation
frameworks.

Highly Desired
• Lead test planning, test case design, and execution for data systems
• Work closely with cross-functional teams for requirement validation
• Participate in Agile ceremonies and drive QA best practices.

Technology Stack:
Primary Skills (Mandatory)

• Advanced SQL (CTEs, Joins, Aggregations, Window Functions)
• Data Analysis and Data Validation
• Cloud Platforms (AWS/Azure/GCP)

Secondary Skills:
• Python for automation and data validation.

Data & Visualization
• Experience validating Tableau dashboards including KPIs, filters, and calculated fields.

Big Data / Cloud Tools
• AWS ecosystem (S3, Athena, Glue, Airflow)
• Exposure to tools like Spark, Kafka is a plus.

Required Qualifications

• 8+ years of experience in software engineering with strong expertise in Java and/or Python
• Proven experience designing and scaling cloud-native applications on AWS
• Deep understanding of distributed systems, microservices, and API-driven architectures
• Strong experience in enterprise integration patterns, including asynchronous and event-driven systems
• Demonstrated ability to design modular, reusable platforms and components
• Experience integrating with enterprise systems such as Salesforce or similar platforms
• Strong knowledge of security, compliance, and access control frameworks
• Excellent communication skills with the ability to influence technical and non-technical stakeholders

Preferred Qualifications

• Experience with healthcare systems (HL7/FHIR)
• Experience with Salesforce integrations
• Exposure to AI/ML and LLM-based applications
• Experience with observability tools and DevOps practices

Success Metrics

• Deliver scalable AWS architectures
• Build reusable platforms to accelerate development
• Reduce system complexity and technical debt
• Improve system reliability and performance
• Drive AI-driven automation and insights

Job Location: Hyderabad, Telangana, India. (Hybrid model - Work from Office).

Why Join Us?

At Guardant Health, we are on a mission to conquer cancer with data. You’ll be part of a team that is revolutionizing precision oncology through cutting-edge technology and innovative software solutions. If you are a technically strong, people-oriented leader who thrives in a collaborative and high-impact environment, we’d love to hear from you!