Formulation Development Scientist: Pharmaceutics and Pre-Clinical Study Support
- Full-time
Company Description
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.
Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.
In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.
In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.
Job Description
- HPLC EXPERIENCE IS REQUIRED
- Development of prototype formulations (solutions, suspensions, dispersions, etc.) for pharmaceutical small molecules for exploratory studies for in vivo models. This activity includes development and characterization of both oral and parenteral dosage forms on small scale with small amounts of material (mg) on rapid timelines.
- Routine preparation and characterization of solution and suspension formulations for use in preclinical efficacy, pharmacokinetic and toxicology studies with novel small molecule therapeutics and derivatives using High performance liquid chromatography (HPLC)
- Measurement of key active compound and formulation properties (such as crystallinity, solubility, dissolution, permeation, stability, self-association, etc)
- Assessment of the chemical and physical properties of small molecules
- Assessment of the performance of prototype formulations using in-vitro tests (dissolution, precipitation, etc.).
- Development of detailed protocols for preparation of formulations at other sites, both internal and external and development and use of formulation problem-solving and troubleshooting skills
- Handling and formulation of high potency/OEB5 compounds using an isolator setup.
- Rapid and detailed documentation of experimental procedures and data in electronic laboratory notebooks.
- Shipment of samples to external sites.
- Routine lab maintenance support (pH meter calibration, mobile phase preparation, etc)
Qualifications
- Experience working with HPLC is required.
- Bachelor’s degree in scientific field (Chemistry/Chemical Engineering, Pharmacy, etc) or other related degree. Alternatively, career experience in pharmaceutical formulation development will be considered.
- Understanding and/or experience in pharmaceutical formulation development
- Excellent communication (oral and written) and keen observation and attention to detail skills.
- Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude.
Additional Information
Position is full-time, Monday - Friday 8:00am - 5:00pm. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
What we offer:
- Excellent full time benefits including comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Yearly goal-based bonus & eligibility for merit-based increases
Eurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries.
We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client’s quality systems and equipment.
To learn more about Eurofins Lancaster Laboratories, please explore our website www.eurofinsus.com.
Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.
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Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.