Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK® (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.   

The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together. 

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care. 

Scientist III is responsible for independently designing, executing, and interpreting biochemical and/or cellular assays to support drug discovery initiatives while working within a cross-disciplinary team environment. The successful candidate will develop and perform primary screening assays for small molecules, perform mechanisms of action studies and/or be responsible for collaborating with stakeholders to troubleshoot innovative workflows and protocols to integrate new technologies to optimize or reduce Design, Make, Test, Analyze (DMTA) cycle time. While primarily serving as an individual contributor, the ideal candidate will also foster a cohesive team environment by managing CRO activities and/or providing mentorship and training to scientists within their areas of expertise. 

Key Responsibilities:  

Assay Development and Experimental Execution (60%) 

• Work collaboratively with biologists, biochemists, and medicinal chemists to deliver high quality data to progress research stage programs 
• Independently develop and optimize novel assays to determine the mechanism of action of small molecules  
• Maintain and calibrate lab equipment to ensure experimental precision and data reproducibility 
• Manage experiments with CRO partners as needed 
• Follow all safety and quality control procedures 

Data Analysis and Documentation (25%) 

• Analyze experimental data and summarize key findings 
• Track and record experiments and data in E-notebooks and LIMS database 
• Generate reports and create presentations as required by the organization 

Collaboration & Support (15%) 

• Work in a cross-functional team environment to achieve shared goals in support of ongoing research projects 
• Provide technical assistance to senior scientists and project leads 
• Mentor and train scientists within area of expertise 
• Other duties and responsibilities as assigned  

• Bachelor’s or Master’s degree in Biological Sciences or related field 
• Minimum of 5+ years for bachelor’s and 3+ years for Master’s of relevant laboratory experience in the biotech or pharma industry  
• Advanced knowledge of biochemical, molecular, and cellular biology techniques  
• Strong background in data analysis and data documentation 
• Ability to manage multiple priorities in a fast-paced research environment 

Preferred Capabilities

• Experience in managing or analyzing research conducted using CRO partners 
• Experience using liquid handling automation platforms 
• Clearly communicate work in both written and spoken forms 

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $90,000-$124,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.​

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.