This is for a 12-week internship position from June – August 2021.

Biogen is seeking a highly motivated intern to join its Analytical Development department focused on the biophysical characterization of gene therapy drug products. The intern will have the opportunity to further characterize gene therapy products in development at Biogen using an array of methods within the biophysical toolbox.

Position Description

The intern will use a variety of high-throughput biophysical techniques to assess the conformation of adeno-associated virus (AAV) products. The goal of the project is to characterize higher-order structural properties of AAVs. A variety of spectroscopic and calorimetric methods will be used including: Circular Dichroism (CD), FTIR, differential scanning calorimetry (DSC), intrinsic tryptophan fluorescence, and static and dynamic light scattering. The effects of DNA packaging on AAV structure and stability will be investigated.

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:

• Legal authorization to work in the U.S.
• Grade point average of 3.2 or higher preferred
• At least 18 years of age prior to the scheduled start date
• Be currently enrolled in an accredited college or university
• Prior laboratory experience

Additional qualifications:

The ideal candidate should have an interest in learning and working in a laboratory and the flexibility to work remotely if needed. Good organization and communication skills are required. An ideal candidate would have experience working with spectroscopic techniques to characterize biomolecules.

Education

Enrolled in an accredited university with an engineering / science disciple. Graduate students and senior undergraduate students will be considered.

All your information will be kept confidential according to EEO guidelines.