Research Assistant, Upstream Process Development

  • Full-time

Company Description

Coherus Biosciences, Inc. is focused on delivering high quality biosimilar therapeutics that will expand the access of important medicines to patients worldwide. Formed in 2010, Coherus has developed a unique, collaborative business model that leverages the leadership team’s deep product development expertise and the expertise of a network of strategic partners to develop therapeutics of the highest quality.  

Our Company is currently looking for a Research Assistant, Upstream Process Development.  This is a newly created position located in Camarillo, California.

Job Description

This position requires at least a Bachelors degree in Biochemistry, Molecular Biology, Biochemical Engineering, or related area. Knowledge of mammalian cell culture, as well as related analytical methods, and aseptic handling techniques is essential.  Knowledge of bacterial fermentation is a plus.

 

 

ESSENTIAL DUTIES AND RESPONSIBILITIES

 

 

  • Performs laboratory experiments related to development of robust upstream processes for manufacturing of human therapeutic proteins produced in recombinant mammalian cells and bacteria

  • Designs, executes, and analyzes experiments at laboratory scale, including shake flasks, spinner tubes, scale down bioreactor systems (Ambr) and bench top reactors (Applikon).

  • Develops and characterizes scaled-down models for upstream unit operations.

  • Possesses knowledge of and experience with cell culturing, handling, counting, media preparation, ELISAs, pipetting, centrifugation, filtration, etc.

  • Responsible for accurate laboratory data entry, lab maintenance and upkeep, and report writing. 

  • Supports identification and optimization of alternative laboratory methods and/or equipment to improve work efficiency and throughput.

  • Retains an up to date knowledge of analytical techniques and relevant scientific literature.

  • Responsible for accurate laboratory data entry, maintenance of necessary documentation and day to day operations. 

  • Keeps Team Leader & Project Manager informed on a regular basis on project status and any circumstances which may alter project scope or established timelines.

Qualifications

EDUCATION AND EXPERIENCE

 

  • BS in Cell Biology, Molecular Biology, Biochemistry, or other relevant area

  • Experience performing a variety of assays including ELISA, IEF gels, PAGE gels and Western blots preferred.

  • Knowledge of technologies related to protein expression.

  • Experience in cell culture process development and Design of Experiment (DOE) a plus.

 

DESIRED KEY COMPETENCIES

 

  • Theoretical knowledge and some practical experience in cell culture as demonstrated by presentations and/or publication record.

  • Participates in solving difficult and complex technical problems.

  • Good communication and presentation skills.

  • Team player.

  • Develops solutions to a variety of complex problems.  Solutions are imaginative, practical and consistent with organization objectives.

  • Plans schedules and lab activities to accomplish objectives.

  • Ability to track and execute on multiple projects simultaneously. 

  • Creative, actively participate in idea generation.

Additional Information

Our Company offers excellent benefits including medical, dental, vision, life, short and long term disability plans, 401k, FSA, vacations, paid holidays and health club reimbursement.  


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