Research Associate, Upstream Process Development
- Full-time
Company Description
Rejuvenate Bio is using a convergent, multi-disciplinary approach, combining gene therapy, proprietary targets, and the animal health market to bring human age-related therapies to market. We are targeting the core drivers of chronic age-related diseases by unlocking the power of gene expression and epigenetic reprogramming to reverse pre-existing heart disease, metabolic disease, and kidney failure in humans.
Each therapy we’re developing has the potential for therapeutic impact across multiple disease indications, with each new piece of data validating the approach and increasing the value of each clinical program. This will allow us to rapidly expand each product into multiple indications. Additionally, our animal health programs provide an untapped market for early revenue and further validation for use in humans.
Job Description
We are seeking a highly motivated Research Associate to join our growing Process Development team! The Research Associate will be responsible for independently performing standard and advanced mammalian cell culture techniques as well as executing experiments to optimize the upstream cell culture process for the production of our AAV gene therapies. Ideal candidates will have experience with adherent or suspension cell culture (any mammalian cell line). This role reports to a Senior member of our Upstream Process Development team.
Responsibilities:
- Following laboratory protocols and safety regulations.
- Performing basic and advanced cell culture on a variety of cell lines (adherent and suspension).
- Executing experiments, independently and in conjunction with a small team in support of research studies.
- Manufacturing AAV and Lenti-virus.
- Working with a team to optimize our SOPs and upstream mammalian cell culture process.
- Performing related laboratory maintenance, such as ordering supplies, managing inventory, and documenting laboratory conditions.
- Performing detailed and accurate documentation of all experiments and laboratory practices.
- Accountable for on-time, high quality results and clear communication with supervisor.
- Plan time appropriately given a set of weekly goals.
- Perform all other duties as assigned by supervisor or manager.
Qualifications
Minimum Qualifications:
- B.S or M.S. in biology, biochemistry, microbiology, biomedical engineering, or related field required.
- At least 1 year of mammalian cell culture experience (suspension or adherent cell lines) during or after undergrad.
- Ability to quickly become independent in daily tasks.
- Ability to discuss results and troubleshoot minor issues.
- Strong work ethic, communication skills and goal-oriented personality.
- Demonstrable experience keeping pristine records of experiments and DNA constructs produced using a digital laboratory notebook.
- Strong problem-solving and critical thinking skills.
Preferred Qualifications:
- Lentiviral or AAV production.
- Experience with suspension cell culture.
- Demonstrated experience leading or assisting on a project or set of experiments in an industry setting.
Additional Information
Base Salary: $65k - $72k; exact salary, job title, and responsibilities will depend on experience.
Physical Requirements:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
- Position is primarily sedentary, and employee may be required to sit for extended periods of time.
- Standing, walking and meeting activities are required frequently throughout the workday.
- Must be able to process paperwork and utilize office equipment (including personal computer, phone, copiers, etc.).
- Normal sight or corrected vision is required to read documents and use standard computer terminals. Some light lifting may be occasionally required.
- Ability to safely and successfully perform the essential job functions consistent with the ADA, FMLA and other federal, state and local standards, including meeting qualitative and/or quantitative productivity standards.
- Ability to maintain regular, punctual attendance consistent with the ADA, FMLA and other federal, state and local standards
- Must be able to lift and carry up to 25 lbs
- Must be able to talk, listen and speak clearly on telephone
EEO Statement
Rejuvenate Bio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Rejuvenate Bio is an E-Verify Employer in the United States. All your information will be kept confidential according to EEO guidelines.
The health and safety of our employees and their families is a top priority. The company encourages employees to remain up-to-date on their COVID-19 vaccinations. Rejuvenate Bio, Inc. employees may be required, in the future, to be vaccinated or have an approved disability/medical or religious accommodation.