Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has commercially launched Guardant360®, Guardant360 CDx, Guardant360 TissueNext™, Guardant360 Response™, and GuardantOMNI® tests for advanced stage cancer patients, and Guardant Reveal™ for early-stage cancer patients. These tests fuel development of its screening program, which aims to address the needs of asymptomatic individuals eligible for cancer screening.

You will be part of the Oncology Division and the Bioinformatics System Software Algorithm team working on and with the software that is used in the clinical laboratory to process patient samples and analyze their genomic profiles, helping to prevent recurrence of cancer for cancer survivors based on a simple blood draw. Your role will be to work with Bioinformatics SQA engineers and members of the bioinformatics group to ensure the quality of bioinformatics software used in CLIA, CAP, NYDOH, and FDA regulated environments and the correct installation on production systems.

Essential Duties and Responsibilities:

• Work with bioinformatics SQA engineers and members of the bioinformatics group to develop test cases that ensure the quality of bioinformatics software used in CLIA, CAP, NYDOH, and FDA regulated environments.
• Participate in requirements and design review meetings to create comprehensive, automated test strategies/plans for bioinformatics software leading to successful implementation and timely project completion.
• Work with the algorithm development team to understand functional specifications, identify and design test cases for sequence analysis software including alignment, variant calling, and annotation software.
• Work with cross-functional teams, and support integration and regression testing of Bioinformatics software.
• Execute complex testing, perform in-depth statistical analysis, and interpret results independently.
• Design, create, enhance, and maintain bioinformatics data simulators and automated testing framework to ensure excellent testing coverage.
• Provide written documentation and specifications of software products and services.
• Provide feedback in a team-oriented atmosphere to design test strategies and test cases with strong knowledge of molecular biology, oncology and bioinformatics.
• Report, track, and escalate anomalies discovered during testing (All testing phases) and ensure closure on issues.
• Perform Impact Analysis for incremental changes and identify the scope of regression / test cycles and execute them as needed.

• Minimum with a BS Degree in Bioinformatics or related field
• Demonstrated experience with programming and scripting languages such as Python, R, C++, shell and RDBMS (SQL or Oracle) and software dev/QA in Linux environment.
• Strong understanding of sequencing data, annotations, and standard bioinformatics tools e.g. samtools, picard, snpEff.
• Demonstrated experience in scripting, running, analyzing, and refining automation frameworks for comprehensive and full application testing, including API testing.
• Demonstrated experience in verifying algorithms, workflow or data analysis software.
• Experience with test case management tools and best practices for scalability and maintainability.
• Experience in Continuous Integration / Delivery tools such as Jenkins and container runtime tools such as Docker
• Excellent organization and people skills with the ability to work across functions to ensure successful integration testing.
• Experience in testing bioinformatics software is preferred
• Experience working in a regulated environment (CLIA, CAP, NYDOH, and FDA) preferred

All your information will be kept confidential according to EEO guidelines.

Covid Vaccination Policy: Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant’s COVID-19 U.S. Vaccination Policy as a reasonable accommodation.  An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the World Health Organization (WHO). In addition, fully-vaccinated employees will be required to maintain their fully-vaccinated status under this Policy by obtaining, if applicable, any FDA-approved boosters.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. 

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.
Please visit our career page at: http://www.guardanthealth.com/jobs/

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