Protein Expression Scientist

  • Full-time

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

Job Description

  • Perform large-scale (up to 10 L) expression of recombinant proteins and virus-like particles (VLPs) by transient transfection of suspension mammalian cells across multiple expression systems, including shake flask and WAVE bioreactor technology
  • Optimize expression conditions for challenging proteins, including multimeric proteins, to improve yield and quality
  • Maintain and expand mammalian cell lines, ensuring proper cell density, viability, and sterility
  • Operate and maintain cell culture analyzers, including the BioProfile FLEX analyzer, to monitor cell culture health and productivity
  • Conduct protein characterization using techniques such as SDS-PAGE, Western blot analysis, and UV-VIS spectroscopy
  • Troubleshoot and resolve issues related to protein expression, cell culture, and equipment operation
  • Maintain detailed records of experiments, protocols, and results under company policies and regulatory requirements
  • Work closely with a lead scientist in the expression group and coordinate with the protein purification and characterization groups in the facility
  • Contribute to the development and optimization of new protein expression protocols and techniques
  • Participate in team meetings and present findings to colleagues and management
  • Ensure compliance with all safety protocols and regulations in the laboratory environment
  • Assist in training junior team members on protein expression techniques and equipment usage

 

Qualifications

Minimum Qualifications:

  • MS in biology, biochemistry or related scientific field. Or BS in biology, biochemistry or related scientific field with 2 or more years of relevant post-graduation work experience in a scientific setting, with preference given to industrial experience
  • Authorization to work in the United States indefinitely without restriction or sponsorship

Preferred Qualifications:

  • Experience with large-scale (up to 10L) suspension mammalian cell cultures and bioreactor technology, including WAVE bioreactor systems
  • Proficiency in cell culture techniques, including sterile aseptic technique, cell passaging, counting, and using cell culture analyzers (e.g., BioProfile FLEX analyzer)
  • Experience with recombinant protein expression by transient transfection of mammalian cells, including optimization for challenging proteins
  • Expertise in protein characterization techniques such as SDS-PAGE, Western blot analysis, and UV-VIS spectroscopy

Additional Information

This position is Full-Time, Monday - Friday, 9:00 a.m. - 5:00 p.m. with overtime as needed and the potential for some off shift hours as dependent on project. Candidates currently living within a commutable distance of West Point, PA are encouraged to apply.

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Privacy Policy