Targeted Lipid Nanoparticle Development Scientist
- Full-time
Company Description
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.
The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.
In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.
In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.
Job Description
he candidate will have a highly visible and integral role towards the process development, scale-up, and manufacturing of Gene Therapy LNPs. The ideal candidate will have experience with lipid nanoparticle formulation, various mixing equipment, TFF system, characterization tools and understanding/knowledge of process parameters. In this highly collaborative and cross functional role, you will help develop/optimize the client process and improve process understanding for multiple programs at various stages of non-clinical development.
Key responsibilities
- Independently and collaboratively design and execute lab studies.
- Summarize experimental results and share scientific insights with cross-functional teams.
- Contribute to the development of targeted lipid nanoparticle (TNP) formulation scale-up processes.
- Perform routine characterizations of LNP/TNP to capture their physical and chemical properties.
- Adhere to GLP and maintain good documentation practices using an electronic lab notebook.
- Assist in organizing and maintaining a clean lab environment.
- Follow documentation and safety protocols.
- Write protocols and technical reports to support formulation development.
Qualifications
- Master’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 2+ years of relevant industrial working experience preferred. Alternatively, a bachelor’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 4+ years of recent relevant industrial working experience.
- Hands-on experience with small-scale LNP formulations using Ignite NanoAssemblr.
- Proficiency in LNP/TNP characterization techniques/assays for size, zeta potential, RNA and protein concentration, pH, osmolality, encapsulation efficiency, etc.
- Experience with mid-scale LNP formulation (T-mixing, IJM) and TFF processes.
- Knowledge of bioconjugation chemistry and antibody conjugates is a plus.
- Understanding of industry practices and standards.
- Strong willingness to learn and collaborate with cross-functional teams.
- Detail-oriented with strong troubleshooting abilities.
- Excellent communication and interpersonal skills.
- Ability to deliver quality results in a timely manner.
- Authorization to work in the United States indefinitely without restriction or sponsorship
Additional Information
Position is Full Time, Monday-Friday, 8am-5pm with overtime as needed. Candidates currently living within a commutable distance of Boston, MA are encouraged to apply..
What we offer:
- Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Yearly goal-based bonus & eligibility for merit-based increases
Eurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ sites dedicated to running and managing laboratory services while eliminating headcount, co-employment, and project-management worries.
We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR, and a great place to work best practices, to recruit, hire, train, and manage highly qualified scientists to perform laboratory services using our client’s quality systems and equipment.
To learn more about Eurofins Lancaster Laboratories, please explore our website www.eurofinsus.com.
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Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.