Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.

Eurofins Discovery is very motivated to apply computational sciences, data visualization, bioinformatics and other data-driven approaches to all steps of the drug development process at every level of the organization. Given the expanding scope of the Research Informatics group's operations, the successful candidate will have the opportunity to continue to build on the existing team to achieve this goal. S/he will be a champion of promoting computational sciences as an integral part of the drug development process.

This individual will be responsible for technical consultation with our chemistry and biology experts and scientists, overseeing and leading scientific data governance, analytical tool development, computational chemistry methods development, and meta-analyses of internal and external data from multiple technologies.

Essential Duties and Responsibilities:

• Represent Computational Chemistry as the subject matter expert for nonclinical research and development;
• Independently pursue research projects, implement novel computational workflows and support a dynamic multi-disciplinary team focused on moving projects from the hit identification stage to the discovery of clinical candidate;
• Contribute to the development, implementation and utilization of state-of-the-art computational software, computer aided drug design and simulation techniques to help drive in silico drug discovery activities;
• Responsible for the analysis, interpretation, integration and reporting of research informatics data generated with internal teams and external clients
• Partner with and support medicinal chemistry team during lead optimization related activities such as docking and scoring of the molecules from rational drug design
• Apply or develop new tools or data-mining techniques for integrative analysis and visualization of large data sets;
• Participate in data governance objectives working closely with IT and the laboratory teams;
• Ensure proper documentation of workflows, reports, tools, and analyses of the Research Informatics’ team;
• Provide transparency and regular communication on project status, potential roadblocks for execution, and new strategies with Technology Sciences leadership;
• Ensures project activities aligns with Eurofins policies, procedures and methodologies;
• Demonstrates and promotes the company vision;
• Regular attendance and punctuality;
• Applies GMP/GLP in all areas of responsibility, as appropriate;
• Conducts all activities in a safe and efficient manner;
• Performs other duties as assigned;
• Owns the accountability and responsibility of delivering to client needs and timeliness;
• Provides cross-functional support to other departments as required;
• Adjusts work hours as needed to meet client deadlines;
• Adheres to site environmental health and safety (EHS) requirements.

Education/Experience (BMQ):

• Ph.D. or equivalent experience in computational chemistry, cheminformatics, or a related discipline
• Experience in using CADD approaches to investigate structural protein-ligand interactions, including homology modeling, pharmacophore modeling, molecular docking, MD simulations
• Knowledge of cheminformatics, bioinformatics and other computational approaches to guide protein-ligand interaction modeling and virtual ligand screening
• Knowledge of methods for structure-based property prediction
• Familiarity with Python scientific programming language and/or scientific workflow systems
• Experience in computational structural biology, including the systematic analysis and use of X-ray crystallographic or cryo-EM data of protein-ligand complexes;
•  Practical working experience in computational chemistry software (e.g. OpenEye, Schrodinger, MOE,  Dotmatics, others) and cloud-based computing;
• Experience with machine learning algorithms and data mining methods.

Ability and/or Skills (BMQ):

• Very good interpersonal relation skills at all levels of the organization, with capability to influence decisions and lead others to achieve results;
• Experience with projects and teams that span multiple time-zones and different cultures;
• Excellent verbal, written, analytical, and presentation communication skills, namely of design rational, key experimental results, issues and accomplishments; adept at communicating a clear vision down, up, and across, effectively aligning resources and motivating teams to achieve goals;
• Proven ability to successfully influence cross-functionally and to be sought after as a technical expert within the computational sciences applied to drug development domain;
• Responsive problem solver and proactive to take actions;
• Details oriented, analytical and investigation skills;
• Ability to multitask with organization, manage own priorities and deliverables, both independently in an the team setting;
• Strong customer focus and ability to manage (internal or external) client expectations;
• Ability to work in a complex international environment;
• Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health.

Additional Preferences:

• Demonstrated ability to work collaboratively in a research program environment and generate hypotheses from computational analysis of data that are strategically aligned with organizational goals and resources;
• A mentor and coach who brings strategical experience building diverse team from scratch to enable long term success for computational sciences applied to Drug Development.

Candidates currently living within a commutable distance of San Diego, CA are encouraged to apply.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.