Scientist I

  • St Charles, MO, USA
  • Full-time

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 50,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialised clinical diagnostics testing.

 In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Essential Duties and Responsibilities:

  • Performs work in a laboratory setting, meeting the physical job requirements of a lab role.
  • Conducts production assays primarily in ADME Toxicology Services, but may support BioMAP®, Immunosignaling, Ion Channel, and/or OncoPanel™ Services based on business needs;
  • Develops Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK applications
  • Develops analytical methods supporting project teams both internally and externally for new assay development.
  • Performs Troubleshooting and Maintenance of Mass Spectrometers and HPLC units. Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
  • Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
  • Provides solutions to more complex problems, identifies and initiates process improvements
  • Maintains high data quality and reproducibility.
  • Performs data and report QC review within the department, and may support study director.
  • Takes ownership of client projects with minimal supervision.
  • Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems.
  • Understands and complies with requirements for work performed at a GxP site.
  • Completes required training and supports 100% of Employee Health and Safety requirements.
  • Demonstrates proficiency with, care and maintenance of lab equipment and department assets.
  • Conducts responsible use of confidential IT and business systems, as required.
  • Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting.
  • Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan.
  • Provides training to colleagues and external end users, when required.
  • Contributes to scientific community, and site research and development objectives.
  • Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives
  • Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines.
  • Routinely communicates project updates to internal and external clients.
  • Performs other duties, as assigned

Qualifications

Basic Minimum Qualifications (BMQ):

  • Direct experience with Liquid Chromatography- Mass Spectrometry and/or ultraviolet spectrometry (LC-MS or LC-UV) in a contract research organization or industry laboratory for ADME/ DMPK applications
  • Demonstrated proficiency in High-Throughput analytical method development for small molecules
  • Direct experience with High Resolution Mass Spectrometry for large molecule analysis for ADME/DMPK/Biotherapeutics applications
  • Demonstrated technical knowledge of Metabolomics in regards to pharmaceutical drug metabolism
  • Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
  • Good communication and interpersonal skills
  • Experience working in a Quality Management System

Education/Experience (BMQ):

  • B.S. with 10 years relevant experience
  • M.S. with 7 years relevant experience
  • Ph.D. with 3 years relevant experience  Or an equivalent of education and experience

Ability and/or Skills (BMQ):

  • Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
  • Ability to perform mathematical calculations, statistical analyses, and data interpretation
  • Ability to multitask with organization and manage time effectively
  • Ability to solve practical problems and troubleshooting skills
  • Ability to work in a laboratory setting, according to physical requirements of a laboratory role
  • Lab equipment and office computer/software proficiency
  • Above average oral and written communication skills
  • Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health
  • Ability to develop new methods, and lead research and development projects
  • Ability to review and QC release data/reports
  • Ability to lead small, informal sub-teams, train, and train new team members
  • Ability to conduct mid-size projects with minimal supervision
  • Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems
  • Ability to easily support cross-functional demands

Additional preferences

  • Scientific expertise with mass spectrometry based quantification for ADME/ DMPK applications in biological matrices.
  • Experience with analytical method development, optimization and method transfer
  • Familiarity with concepts of validation of bioanalytical methods in accordance with regulatory (FDA, ICH) guidelines
  • Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening
  • Experience in small team leadership and project management
  • Experience in leading and delivering results in R&D or innovation programs

Additional:

  • For all Eurofins Discovery Services Businesses in US; Successful applicants will be required to confirm vaccination status or demonstrate eligibility for medical or religious exemptions prior to commencing employment.

Additional Information

Candidates currently living within a commutable distance of St. Charles, MO are encouraged to apply.

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

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