About This Role

We are looking for a highly motivated individual to join the Immunology Research Unit at Biogen.

The successful candidate will join an outstanding team of scientist focused on the investigation of immunological mechanisms leading to inflammation and autoimmunity in order to develop new therapies for autoimmune disorders.

What You’ll Do

• Design and execute experiments critical for target validation; in vitro and in vivo pharmacology (PK/PD)
• Investigation of lead molecules in mouse animal models; perform injection (orally; i.v; i.p), animal handling, immunization, clinical scoring, and tissue collection
• Perform functional T and B cell assays using rodent and human peripheral blood mononuclear cells
• Perform tissue- immune cell isolation ((monocyte/dendritic cells, T, B, and NK cells)
• Use a wide array of techniques (Flow Cytometry, FACS, ELISA/MSD, WB, and IHC,)
• Drive drug discovery efforts for Immunology and Autoimmunity
• Independently design and execute experimental plans. Perform rigorous analysis and interpretation of experiments
• Deliver and present the experimental results to the Immunology Research Unit and cross-functional teams.
• Participate on research teams in early target discovery and work to advance programs to R&D
• Involvement in laboratory management and organization

Who You Are

You love discovery and are passionate about using data to drive research decisions and build new therapeutic indications. You love learning new technological skills and working through collaboration. An individual who is self-motivated, dynamic, and thrives in a highly matrixed group.

Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

Required Skills

Qualifications

• Background in Autoimmunity is ideal
• Flow cytometry, cell sorting, and fluorescence microscopy
• Western blot/Jess, ELISA/MSD
• Primary cell (human and mouse) isolation, culturing, and in vitro cell-based assays (T, B, NK cell assays)
• RNA isolation and qPCR
• Bulk/single cell RNA seq
• Proficient in Microsoft office applications, Flowjo, and Prism
• Expertise in spatial tissue-based transcriptomic, proteomics & lipidomics is a plus
• Data analysis (e.g., R) is a plus

Education

• Ph.D. in a life-science field: Immunology, Neuroimmunology, Cell Biology
• Or M.S. with relevant drug discovery expertise and track record of accomplishment

*LI-RD8

All your information will be kept confidential according to EEO guidelines.

Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.