At Biogen, our mission is clear - we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population. 

We at Biogen are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients who we serve. We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included.

As an intern or co-op at Biogen, you can expect to be placed on a real project, under the guidance of experienced professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.

This application is for a full-time internship role from June - August 2022. Resume review begins in January 2022.

We are looking for highly motivated students to join our Physical Biochemistry group within the department of Biotherapeutic and Medicinal Sciences at Biogen for a summer internship. The successful candidate will be part of a fast-paced and innovative environment actively pursuing unmet medical needs in the neuroscience space.

When you submit your resume, you may be considered for one of the following intern positions:

• Protein Purification: The candidate will express and purify recombinant target proteins and biophysically characterize them.
• NMR screening: The candidate will work with other NMR scientists in hit finding and characterize small molecule complexes with nucleic acids and proteins using NMR.
• Structural biology: Depending on interest and experience, the candidate will work on all steps of the structural biology pipeline, from protein expression and purification to structural characterization via crystallography and/or cryo-EM (both on site) and map and model building, refinement, and analysis.

The successful candidate should have several of the qualifications below: 

• Molecular Biology: Classroom study with laboratory preferred. May possess working knowledge of construct design and basic molecular biology (PCR & cloning)

·        Protein Purification: Candidate should have experience with expression and purification of proteins from E. coli, insect, or mammalian hosts with use of Akta Express, Avant or equivalent protein purification systems. Must be adept at following established protocols for multi-step purifications and will work toward achieving independence in cell culture techniques and protein purification. The candidate should also possess the scientific understanding behind the protocols and be able to modify them when the need arises.

• Spectroscopy: Basic understanding of biophysical analytical techniques including but not limited to the following: microscopy, mass spectrometry, NMR, ITC, etc
• Structural Biology: Understanding of protein structure fundamentals and familiarity or experience with techniques including crystallography, electron microscopy (negative stain and cryo-EM). Basic Linux skills preferred, and experience with model building and refinement a plus.
• Ability to troubleshoot and solve scientific and technical problems. The candidate should be willing to quickly learn new techniques.
• Must be excellent in organization and communication skills. The candidate is expected to document all aspects of the experiments performed and be able to conduct independent research to collect and archive all necessary information.
• Innovative approaches to problem solving will be highly valued.

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:

• Legal authorization to work in the U.S.
• At least 18 years of age prior to the scheduled start date
• Be currently enrolled in an accredited college or university

Education

Education: Current undergraduate or graduate students pursuing degrees in Biochemistry, Molecular Biology, Biophysics, Chemistry, or a related discipline.

All your information will be kept confidential according to EEO guidelines.