This is for a 6-month position from July - December 2021.

We are seeking a Co-op to join Biogen’s Biologics Drug Discovery Team, and contribute to our mission to design, optimize, and develop therapeutics to improve the lives of patients with neurodegenerative diseases. In this role, you will contribute to a cross-functional effort to identify and validate novel technologies and modalities for enhancing systemic delivery of therapeutic candidates to the central nervous system (CNS).

Position Description:

Performing in vitro quantitative assays to support assessment of CNS delivery/ targeting properties of biotherapeutics: Meso-Scale Discovery-Electrochemiluminescence (MSD-ECL) or ELISA based assay to measure concentration of therapeutic antibodies in tissue culture media from in vitro functional assays as well as in rodent serum and tissue extracts from in vivo studies. Other activities will include maintaining cell culture lines and cell-based transwell model systems, as well as assessment of cell-surface receptor binding for BBB targeted antibodies using flow cytometry. Quantitative data analysis using Excel, Prism or other relevant software systems and reporting will be expected. Previous cell culture experience is preferred. There will also be an opportunity to receive in vivo training and participation in rodent CNS biodistribution studies.

To participate in the Biogen Intern or Co-op Program, students must meet the following eligibility criteria:

• Legal authorization to work in the U.S.
• Enrollment in a full-time undergraduate or graduate program, returning to the academic program following Biogen Intern or Co-op assignment
• Minimum grade point average of 3.2 preferred
• At least 18 years of age prior to the scheduled start date
• Completed at least one year of undergraduate studies

Additional qualifications:

• Familiarity with MSD-ECL or Elisa techniques. Basic knowledge on Excel, Prism and other relevant software systems.

Education

Juniors/Seniors majoring in biology, biochemistry, neuroscience or relevant fields

All your information will be kept confidential according to EEO guidelines.