Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle® Drug Conjugate (BDC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radioconjugates (BRC®) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.

Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, Massachusetts, US. For more information, visit bicycletherapeutics.com.

Culture is key and all Bicycle employees actively embrace and role model our company values: 

• We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.   
• We are Dedicated to our Mission. You can’t change the world if you don’t have determination. 
• We are One Team. We only succeed when we work together.  

The Laboratory Operations Associate is a critical role responsible for the seamless and efficient functioning of our laboratory and logistics operations. This position provides essential, hands-on support to the scientific teams through direct laboratory assistance, while also managing the end-to-end logistics of laboratory supplies, from receiving goods to inventory control and stock management.

By maintaining a safe, compliant, and well-serviced environment, the holder of this position will be a key enabler of our research and development activities, ensuring our scientific staff can focus on their core mission. As a vital member of the Lab & Facilities team, you will be self-motivated and proactive, ensuring a high-quality, reliable service is delivered across all areas of responsibility.

Key Responsibilities: 
Lab Support:

• Provide practical lab support for the Biology and Chemistry Teams, acting independently to complete routine support functions, including:
• Ensure glassware is collected, cleaned, and autoclaved.
• Preparation of lab coats for laundry with an external supplier.
• Prepare basic solutions, culture media, agar plates and buffers.
• Ensure waste is appropriately collected and disposed of via appropriate waste streams.
• Manage requests through the ticketing system - prioritise tasks by their importance and to plan the best strategy for completing those tasks as well as liaising directly with scientists to discuss their support requirements.
• Compressed gases management – LN2 and gas cylinder maintenance.

Logistics and Inventory Management:

• Receipting, unpacking and storing inbound goods correctly, in accordance with SOPS, as well as temperature and safety requirements.
• Filing, storage and timely upkeep of delivery records.
• Maintaining an accurate inventory of lab essential stock, ensuring regular stock checks are performed to determine trends in stock levels and leads times.
• Placing orders to ensure continual supply of inventory catalogue items.
• Liaising with finance and accounting team to investigate and rectify discrepant / erroneous deliveries and invoices.
• Maintenance of the Goods In Area, Delivery yard and stores to ensure it remains safe, fit for purpose and accessible for all users.
• Professionally manage interactions with couriers and other contractors using this area.

Performing other occasional tasks fitting this grade and the skill set of the individual may also be required by this role, including covering main reception desk and meeting visitor to site.

Key Skills & Competencies 

Essential:  

• A-level education including science subjects, or equivalent with a demonstrable interest in science.
• Excellent organizational skills with a high level of attention to detail.
• Proven ability to prioritise and manage multiple competing demands to provide a seamless service.
• Proactive, independent and self-motivated, with the initiative to identify opportunities for process improvement.
• Strong interpersonal and communication skills, with a professional approach to dealing with internal teams and external contacts.
• Computer literate, including using software such as Microsoft Excel, PowerPoint and Word, and comfortable learning new IT systems.

Desirable:  

• Previous experience working in a busy laboratory or scientific environment.
• Experience in a goods-in, inventory management, or warehouse role.
• Hands-on experience with specialist software tools e.g. ticketing systems, purchasing software

• State-of-the-art campus environment with on campus restaurant and The Old Station Nursery 
• Flexible working environment
• Competitive reward including annual company bonus
• Employee recognition schemes
• 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually
• Employer contribution to pension (employee does not have to contribute)
• Life assurance cover 4x basic salary
• Private Medical Insurance, including optical and dental cover
• Enhanced parental leave policies
• Group income protection
• Employee assistance program
• Health Cash Plan
• Access to company subsidized gym membership
• Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.
• Cycle to work scheme

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.